2-Hydroxypropyl-β-cyclodextrin CAS 128446-35-5

2-Hydroxypropyl-β-cyclodextrin CAS 128446-35-5

2-Hydroxypropyl-β-cyclodextrin one of the most widely used cyclodextrin derivatives. It is mainly used in food, medicine, cosmetics industry.

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Product Details

Product name: 2-Hydroxypropyl-β-cyclodextrin

CAS No.: 128446-35-5

Molecular formula:C63H112O42

Formula weight: 1541.54

Constitutional formula:

Function of 2-Hydroxypropyl-β-cyclodextrin: 2- Hydroxypropyl-β-cyclodextrin is an ideal injection solvent and drug excipient. It can improve the water solubility of insoluble drugs, increase the stability of drugs, improve the bioavailability of drugs, increase the curative effect or reduce the dosage of drugs, adjust or control the release rate of drugs, and reduce the side effects of drugs.


Specification of 2- Hydroxypropyl-β-cyclodextrin:

Item

Specification

Test result

Appearance

White or  almost white, amorphous or crystalline powder. Freely soluble in water and propylene glycol

Conforms

Identification

IR:same absorption bands as USP Hydroxypropyl

Betadex RS

Conforms

Clarity of solution :Positive

Conforms


Molar substitution

0.40-1.50

0.66

Betadex

≤1.5%

0.3%

Propylene glycol

≤2.5%

0.1%

Any other single impurity

≤0.25%

Not detected

Total impurities excluding betadex and propylene glycol

≤1.0%

Not detected

Propylene oxide

≤1ppm

0.05ppm

Loss on drying

≤10.0%

3.0%

Assay

≥99.5%

99.51%

Clarity of solution

1.0g/2ml water solution is clear and transparent

Conforms

Conductivity

≤200ʯS/cm

108ʯS/cm

The total aerobic microbial count

≤1000cfu/g

<10cfu/g

The total combined moulds and yeasts count

≤100cfu/g

<10cfu/g

Packaging and storage

Preserve in well-closed containers.Store at room temperature.


Conclusion: conform to USP42


Packing of 2-Hydroxypropyl-β-cyclodextrin:

201801181500479868012


Delivery way:

201801181500508838170

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