CAS No. : 97240-79-4
Chemical structural formula:
Function:The major mechanism of Topiramate is through blocking the dispersion of epileptic seizures rather than preventing its occurrence. It has been also found that TPM can exert its efficacy in treating epilepsy through various kinds of mechanisms including:
1, blocking the voltage-dependent sodium channels and thereby reducing the duration of epileptic discharges and the number of action potentials generated during each discharge.
2, antagonizing kainate/AMPA--glutamate receptors.
3, enhancing the GABA activity in the non-benzodiazepine position of the GABA receptor.
4, mildly inhibiting carbonic anhydrase.
5, blocking the T-type calcium channels.
6, block the activity of the excitatory neurotransmitter of the central nervous AMPA glutamate receptor.
Storage :Store in a cool and dry place, protected from light, keep drum close when not in use.
COA and MSDS
Packing of Topiramate:
Delivery of Topiramate: